It also offers information about side effects and interactions with other drugs, and answers questions about related cancer risks from using it. Testosterone enanthate is classified as an AAS for two reasons. It is both a synthetic drug derived from the testosterone hormone and a testosterone pro-drug.
This means it stimulates the body to make its own testosterone. With that being said, it has stronger androgenic effects and only moderate anabolic effects. The drug can be used for testosterone replacement therapy TRT in cisgender cis men with hypogonadism , or the decreased ability to make testosterone.
Causes of this condition include injury, infection, and cancer of the testes. Radiation and chemotherapy can also cause hypogonadism. So can disorders such as Klinefelter syndrome and diseases of the hypothalamus and pituitary gland, two brain regions that stimulate the testes to make testosterone. Testosterone levels in cis men can drop steeply after the age of 50, leading to a condition known as andropause.
Older cis men with symptoms of andropause, including the loss of vigor and a lower sex drive, will often benefit from TRT. This drug can also be used for hormone therapy in transgender masculine people. Other uses include treatment for delayed puberty in cis boys, and in metastatic breast cancer when it has spread in those who are postmenopausal. The drug is also sometimes used, controversially, as an anti-aging therapy in older cis men. Testosterone enanthate is a clear or yellowish fluid that comes in a 5-milliliter ml glass vial.
It is injected into a buttock muscle every one to four weeks. To avoid large changes in hormone levels, and the mood swings that may come with them, lower doses are often used over shorter intervals. The active drug, which is suspended in sesame oil, has a sustained release period of two to three weeks. The dosage may vary by individual but it is typically used as follows:. While testosterone enanthate is sometimes used interchangeably with testosterone cypionate depo testosterone , the latter is approved only for treating hypogonadism.
Testosterone enanthate is a steroid with both anabolic and androgenic properties. It is used to treat low testosterone levels, whether as TRT in cisgender men or as hormone therapy in transgender people, among other uses. It is given by intramuscular injection in the buttocks. This drug is designed to alter hormone levels, and has both clear benefits and risks. The side effects can range from mild to intolerable. The most serious side effects are associated with testosterone abuse, an increasing problem in the United States.
According to the FDA, the most common side effects associated with testosterone enanthate use include:. The severity of the side effects usually depends on the dose. The side effects may improve if the dose is reduced.
Less common but potentially more serious side effects are associated with the long-term use or overuse of this drug. Some are related to its androgenic effects. Others can affect the heart and liver. Call a healthcare provider if you have any of the following while using testosterone enanthate:. Some androgenic effects seen in those assigned female at birth, such as clitoral enlargement and a deepening voice, are permanent once they happen.
A low sperm count can reduce fertility in cis men. The excessive use of testosterone also may increase the risk of some medical conditions, especially in cis men. They include:. Severe liver injury also may occur. Symptoms of such injury include fatigue, abdominal pain, nausea, vomiting, dark urine, and the yellowing of the eyes and skin jaundice. Call or seek emergency care if you have signs of a cardiovascular event, such as heart attack or stroke.
Heart attack signs include chest pain, shortness of breath, profuse sweating, and pain in the left arm or jaw.
Stroke symptoms include severe headache, weakness on one the side of the body, and trouble speaking. There are certain drugs that interact with testosterone enanthate. Some may need to be changed or adjusted. Or, other forms of therapy can be explored, including lower-dose testosterone patches. The possible drug interactions include:. There are conditions in which this drug should not be used under any circumstances.
This includes the use of testosterone in untreated prostate cancer or breast cancer , and in pregnancy. The drug should also be avoided if you are allergic to sesame oil or any components of the drug. The prostate gland is an organ in those assigned male at birth. Its role is to secrete prostate fluid, one of the elements of semen. The total lifespan persists a maximum of 72 hours.
Testosterone, like other estrogen compounds, absorbs poorly and metabolizes quickly. Propionate leaves the system entirely by day The short duration of propionate makes it time-consuming.
It is the most work-intensive ester compound for treatment regiments. Injections need to be done daily to maintain levels and drop-offs occur in as little as 2 days after stopping.
Propionate compounds are used by bodybuilders or athletes. It has a discernable effect in building muscle mass. It also leaves the system fast enough to avoid doping test issues. Enanthate works as a middle ground between cypionate and propionate. Effects hit between 24 and 48 hours, like cypionate.
The duration lasts 4 days of peak and 10 days in total. You need to inject enanthate every 3 days, maximum, to maintain consistent levels. Enthanate compounds stay detectable in the system for 22 days.
The tests for anabolic steroids, of which all the previous esters qualify, look for the ester bonds. To find the duration of a BHRT duration you need to test for a baseline hormone level and then for when that baseline returns.
When undergoing BHRT as part of a hormone optimization plan, these levels get tested frequently in saliva or blood tartrate tests. BHRT hits less hard, as a process it is about steady function, not peak performance. Typically injections get performed every two weeks.
This provides double the duration of the cypionate ester. BHRT also has the benefit of being indiscernible from natural testosterone production. This best testosterone injection keeps levels in the upper range of normal to benefit you. Drop-offs occur after the age of 20 and accelerate after Worse, by 40 levels are half of what they were at Low testosterone Low T diagnosis have risen from better testing methods.
They have also risen from awareness of the underlying processes. Testosterone controls a lot of systems for men and some for women, mostly from adrenal production. Long-term health concerns from lack of muscle mass and bone density have made monitoring levels important. Fat metabolization and usage are also keys to avoiding diabetes and heart disease. On the mental side, issues of mood and especially depression have emerged. Low T leads to a lower quality of life as physicality drops off and mood deteriorates.
Each of these problems alone is a cause for concern. When put together, they form a brutal loop for men. The lack of physicality increases as the desire to stay active declines.
Once they physicality tapers enough the ability to stay active in important life activities like work and home fades. Stick with it and you should soon see improvements in many other aspects of your life.
You should notice a reduction in depression after three to six weeks, although it might take several months to fully recover. For men who have diabetes, or pre-diabetes, testosterone replacement therapy may bring dramatic and rapid improvements. After just a few days, your insulin sensitivity could measurably improve. However, full blood sugar control takes longer often between three and twelve months.
Continue taking your diabetes medications even if you feel better, and visit your doctor regularly to find out whether you need to adjust your dose. Although the first testosterone therapy effects appear quickly, you need to keep up with the course of treatment for an extended period of time to reap the full benefits.
Your sex life should improve over time as you receive testosterone replacement therapy. Although most men notice increased interest in sex after just a few weeks, it could take as much as six months for your erections to improve firmness. Taking TRT for several months can change the way your body looks. After three or four months , you should notice an increase in lean body mass.
You might also notice that you have a little less fat. These changes occur because testosterone makes the body prioritize building muscle over putting down fat stores. If you regularly work out in the gym, you might notice your muscles getting stronger so you can lift heavier weights.
Perhaps the slowest-acting benefit of TRT is its effect on your bones. Studies show that men taking testosterone have measurably stronger bones after six months on the therapy.
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